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ABPath Hematopathology Practice Questions - ABPath Hematopathology Subspecialty Certification Exam

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About this Exam

Prepare with the ABPath Hematopathology Practice Questions - ABPath Hematopathology Subspecialty Certification Exam practice quiz. This question bank includes 100 questions covering shows, diagnosis, year-old, cells, and marrow. Use it to review important concepts, identify knowledge gaps, and build confidence for the related exam, course, or assessment.

Sample Questions

Question 1
A 65-year-old man presents with bruising and bleeding. Peripheral smear shows hypergranular promyelocytes with Auer rods (some faggot cells). Cytogenetics show t(15;17)(q24;q21). The most likely diagnosis is:
Acute myeloid leukemia with RUNX1-RUNX1T1
Acute promyelocytic leukemia (APL) with PML-RARA
AML with inv(16)
Chronic myeloid leukemia
Question 2
A 30-year-old woman presents with fatigue. CBC shows WBC 45,000/μL with neutrophilia, basophilia, and left shift with blasts <10%. Cytogenetics show t(9;22)(q34;q11) creating BCR-ABL1. The most likely diagnosis is:
Chronic myeloid leukemia (CML), chronic phase
Acute lymphoblastic leukemia
Myelodysplastic syndrome
Essential thrombocythemia
Question 3
Peripheral blood flow cytometry in a 70-year-old with lymphocytosis (ALC 15,000/μL) shows a B-cell clone with CD19+, CD5+, CD23+, CD20 dim, FMC7-, surface kappa dim. The diagnosis is:
Monoclonal B-cell lymphocytosis (MBL)
Chronic lymphocytic leukemia (CLL) — because the absolute monoclonal B-cell count is ≥5,000/μL per iwCLL 2018 criteria
Mantle cell lymphoma
Follicular lymphoma
Question 4
A lymph node flow on a 62-year-old man shows a B-cell clone with CD19+, CD5+, CD23-, CD20 bright, FMC7+, kappa restriction. IHC shows cyclin D1+ and SOX11+. The most likely diagnosis is:
CLL/SLL
Mantle cell lymphoma (MCL)
Diffuse large B-cell lymphoma
Follicular lymphoma
Question 5
A lymph node shows follicular architecture with tightly packed, small follicles containing centrocytes and centroblasts. Flow: CD19+/CD10+/BCL6+/BCL2+/CD5-. Cytogenetics: t(14;18)(q32;q21). The diagnosis is:
Reactive follicular hyperplasia
Follicular lymphoma (FL)
Mantle cell lymphoma
Marginal zone lymphoma

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Additional Information

ABPath Hematopathology Practice Questions - ABPath Hematopathology Subspecialty Certification Exam

This practice set contains 100 questions from the matching question bank and focuses on shows, diagnosis, year-old, cells, and marrow. Work through each question carefully, review the provided solutions, and revisit topics that need more study before your next attempt.

This is an independent study resource intended for practice and review; it is not an official examination or an endorsement by any organization named in the title.

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Frequently Asked Questions

This quiz contains a total of 100 practice questions carefully selected to test your knowledge on this subject.
Yes, you will have exactly 0 minutes to complete the exam. A countdown timer will be visible once you start.
Yes, you can retake this practice test as many times as you need. The questions and options may be randomized on subsequent attempts to ensure comprehensive learning.

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