CITI HUMAN SUBJECTS
RESEARCH
CERTIFICATION PRACTICE
EXAM 85 QUESTIONS
COMPLETE
Question 1: Which set of principles forms the ethical framework of the Belmont
Report?
Choices:
1) Respect for Persons, Bene�cence, and Justice 2) Autonomy, Fidelity, and Veracity 3) Privacy, Con�dentiality, and Security 4) Scienti�c Merit, Equipoise, and Transparency
Correct Answer: Respect for Persons, Bene�cence, and Justice
Explanation: The Belmont Report identi�es Respect for Persons, Bene�cence, and Justice as the three basic ethical principles for research involving human subjects.Page 1
Question 2: A protocol excludes older adults solely because recruitment would be easier among university students, even though the disease being studied mainly a�ects older adults. Which Belmont principle is most directly implicated?
Choices:
1) Respect for Persons 2) Justice 3) Bene�cence 4) Con�dentiality
Correct Answer: Justice
Explanation: Justice requires fair distribution of the burdens and bene�ts of research and equitable subject selection. Excluding the population most a�ected merely for convenience can create an unjust distribution.Question 3: Which historical development was a direct result of the U.S. National Research Act of 1974?
Choices:
1) Creation of the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research 2) Adoption of the Nuremberg Code by the United States as federal law 3) Creation of the Food and Drug Administration 4) Enactment of the HIPAA Privacy Rule Correct Answer: Creation of the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research Explanation: The National Research Act created the National Commission, which later issued the Belmont Report and helped shape modern U.S. human-subject protections.Page 2
Question 4: What core requirement is emphasized in the Nuremberg Code?
Choices:
1) Voluntary consent of the human subject 2) Mandatory compensation for every research injury 3) Automatic exclusion of all vulnerable populations 4) Federal registration of every observational study
Correct Answer: Voluntary consent of the human subject
Explanation: The Nuremberg Code prominently states that voluntary consent of the human subject is essential, re�ecting a foundational concern for autonomy and freedom from coercion.Question 5: Why is Henry Beecher's 1966 article important in the history of research ethics?
Choices:
1) It demonstrated that serious ethical problems in human research were not limited to wartime atrocities 2) It created the �rst federal IRB regulations 3) It established the HIPAA Privacy Rule 4) It replaced the Belmont Report Correct Answer: It demonstrated that serious ethical problems in human research were not limited to wartime atrocities Explanation: Beecher described ethically troubling studies conducted in respected U.S.institutions, showing that unethical research practices could occur in ordinary academic and clinical settings.Page 3