COLLIN COLLEGE
CARDIAC DRUGS
PRACTICE TEST 40
QUESTIONS
Question 1: A patient asks how lisinopril lowers blood pressure. Which explanation is most accurate?
Choices:
1) It inhibits conversion of angiotensin I to angiotensin II 2) It blocks beta1 receptors in the heart 3) It blocks calcium entry into vascular smooth muscle 4) It directly increases sodium excretion in the loop of Henle
Correct Answer: It inhibits conversion of angiotensin I to angiotensin II
Explanation: Lisinopril is an ACE inhibitor. By reducing formation of angiotensin II it decreases vasoconstriction and aldosterone-mediated sodium retention which lowers blood pressure.Page 1
Question 2: A patient taking Zestril (lisinopril) develops a persistent dry cough.Which interpretation is most appropriate?
Choices:
1) The cough proves the patient has pulmonary edema 2) The cough is a recognized ACE inhibitor adverse e�ect 3) The dose is too low to control hypertension 4) The �nding is typical of digoxin toxicity Correct Answer: The cough is a recognized ACE inhibitor adverse e�ect Explanation: A persistent nonproductive cough is a well-known adverse e�ect of ACE inhibitors such as lisinopril and is related to increased bradykinin.
Question 3: Which laboratory value deserves particular attention in a patient
receiving lisinopril?
Choices:
1) Serum calcium 2) Serum uric acid only 3) Serum potassium 4) Serum amylase
Correct Answer: Serum potassium
Explanation: ACE inhibitors can decrease aldosterone activity and cause hyperkalemia.Potassium and renal function should be monitored during therapy.Page 2
Question 4: Which patient statement about lisinopril requires immediate correction?
Choices:
1) I will rise slowly if I feel dizzy 2) I will report swelling of my lips or tongue 3) I will ask before using potassium supplements 4) I can continue this medicine if I become pregnant
Correct Answer: I can continue this medicine if I become pregnant
Explanation: ACE inhibitors carry fetal toxicity risk and should be discontinued as soon as pregnancy is detected unless a clinician determines otherwise for an exceptional circumstance.
Question 5: Losartan lowers blood pressure primarily by which action?
Choices:
1) Blocking angiotensin II receptors 2) Blocking cardiac sodium channels 3) Stimulating beta1 receptors 4) Inhibiting platelet P2Y12 receptors
Correct Answer: Blocking angiotensin II receptors
Explanation: Losartan is an angiotensin II receptor blocker (ARB). It blocks the e�ects of angiotensin II at AT1 receptors and reduces vasoconstriction and aldosterone e�ects.Page 3